Eddie Brock is back and trying to be a hero as Anti-Venom. But even as Eddie and Spidey tentatively team up to take down Mr. Negative, they have to figure out if the returned Wraith is friend or foe. Then: welcome to Spider-Island, where a million New Yorkers suddenly possess Spider-Man's powers. Can Spidey play world-saving super hero while the Big Apple gets eaten alive from the inside out?